The BrainWise Program is the recipient of support from a wide range of donors, foundations, government agencies, and other supporters.

In 2007 the BrainWise Program was awarded a Capacity Building Grant by the Department of Health and Human Services to help expand its base and enable it to reach more programs and schools.

International support to fund operations in China has been received from the Institute of International Education, the Ford Foundation, Save the Children - UK, and the Yunnan Reproductive Health Association. Dr. Li Xiaoliang, a BrainWise instructor in China, has translated the curriculum into Chinese and it has been published there with the support of these agencies. These resources have also allowed the training of Chinese educators and the program is being taught in rural areas of the country.

In the United States, these are some of the foundations, corporations, and agencies who have been major supporters of the BrainWise Program:

• Anschutz Family Foundation
• Audrey K. Dines Memorial Fund
• Charles J. Beaird Foundation
• Colorado Children's Trust Fund
• Coors Foundation
• The Denver Foundation
• The Donnell-Kay Foundation
• Hunt Alternatives Fund
• Junior League of Denver
• Kenneth Kendall King Foundation
• Lucent Technologies
• Maidie Foundation
• Rose Community Foundation
• Safe and Drug Free Schools Program
• Telephone Pioneers of America
• Temple Hoyne Buell Foundation
• TYL Foundation
• US West Foundation
• WB2 Charities
• West Denver Teen Pregnancy Prevention
• Women's Foundation

Revenue generated from the sale of BrainWise products is used to subsidize program costs at inner city schools and help pay for the agency's operating expenses. In addition, by outsourcing and using volunteers to supplement its operations, the agency has determined that over 90% of its revenue is spent on the development, production, implementation and evaluation of the BrainWise Program.